Frondoside A is a triterpenoid glycoside from the Atlantic Sea Cucumber, Cucumaria frondosa.Frondoside A has a broad spectrum of anti-cancer effects, including induction of cellular apoptosis, inhibition of cancer cell growth, migration, invasion, formation of baby lock spirit embroidery machine price metastases, and angiogenesis.In cell lines and
Estrogen receptors (ESR1 and ESR2) play crucial roles in various processes during spermatogenesis.To elucidate individual roles of ESRs in male fertility, we developed in vivo selective ESR agonist administration models.Adult male rats treated with ESR1 and ESR2 agonist for 60 days show spermatogenic defects leading to reduced sperm counts and fert
What factors predict the originality of domain-specific idea generation? Replicating and extending an earlier study using a Design Product Ideation task in an introductory university design course, the present research, grounded in the componential theory of creativity, assessed the relative contributions to originality of design ideation from five
Roberts Syndrome (RBS) and Cornelia de Lange Syndrome (CdLS) are severe developmental maladies that present with nearly an identical suite of multi-spectrum birth defects.Not surprisingly, RBS and CdLS arise from mutations jomeed furniture within a single pathway--here involving cohesion.Sister chromatid tethering reactions that comprise cohesion a